Southwest Airlines
WN-692
20:15
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
20:55
05/11/2026
STL
St Louis Lambert International Airport
₹13,353
per person
Select →
✕ Non-refundable 10 fare options
Southwest Airlines
WN-2361
07:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
07:45
05/11/2026
STL
St Louis Lambert International Airport
₹13,353
per person
Select →
✕ Non-refundable 10 fare options
Southwest Airlines
WN-2141
20:30
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
2h 15m
1 Stop
⏱ MDW · 0h 45m MDW Airport
22:45
05/11/2026
STL
St Louis Lambert International Airport
₹14,457
per person
Select →
✕ Non-refundable 10 fare options
Southwest Airlines
WN-878
13:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
5h 55m
1 Stop
⏱ MDW · 4h 30m MDW Airport
18:55
05/11/2026
STL
St Louis Lambert International Airport
₹14,987
per person
Select →
✕ Non-refundable 5 fare options
American Airlines
AA-5013
08:21
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
3h 26m
1 Stop
⏱ ORD · 1h 14m ORD Airport
11:47
05/11/2026
STL
St Louis Lambert International Airport
₹16,789
per person
Select →
✓ Refundable 26 fare options
American Airlines
AA-3579
17:32
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
4h 47m
1 Stop
⏱ ORD · 2h 39m ORD Airport
22:19
05/11/2026
STL
St Louis Lambert International Airport
₹16,789
per person
Select →
✓ Refundable 26 fare options
American Airlines
AA-1259
06:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
5h 47m
1 Stop
⏱ ORD · 4h 0m ORD Airport
11:47
05/11/2026
STL
St Louis Lambert International Airport
₹16,789
per person
Select →
✕ Non-refundable 26 fare options
American Airlines
AA-3387
05:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
3h 27m
1 Stop
⏱ ORD · 1h 39m ORD Airport
08:27
05/11/2026
STL
St Louis Lambert International Airport
₹16,789
per person
Select →
✕ Non-refundable 25 fare options
American Airlines
AA-1259
06:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
2h 27m
1 Stop
⏱ ORD · 0h 37m ORD Airport
08:27
05/11/2026
STL
St Louis Lambert International Airport
₹16,789
per person
Select →
✕ Non-refundable 25 fare options
Southwest Airlines
WN-878
13:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
2h 25m
1 Stop
⏱ MDW · 1h 0m MDW Airport
15:25
05/11/2026
STL
St Louis Lambert International Airport
₹18,360
per person
Select →
✕ Non-refundable 10 fare options
Southwest Airlines
WN-2587
08:40
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
4h 15m
1 Stop
⏱ MDW · 2h 40m MDW Airport
12:55
05/11/2026
STL
St Louis Lambert International Airport
₹18,360
per person
Select →
✕ Non-refundable 10 fare options
Southwest Airlines
WN-4845
05:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
5h 15m
1 Stop
⏱ BWI · 2h 30m BWI Airport
10:50
05/11/2026
STL
St Louis Lambert International Airport
₹18,360
per person
Select →
✕ Non-refundable 10 fare options
Southwest Airlines
WN-1853
16:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
4h 55m
1 Stop
⏱ BNA · 2h 55m BNA Airport
20:55
05/11/2026
STL
St Louis Lambert International Airport
₹18,360
per person
Select →
✕ Non-refundable 10 fare options
Southwest Airlines
WN-1282
15:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
7h 5m
1 Stop
⏱ DEN · 2h 50m DEN Airport
22:05
05/11/2026
STL
St Louis Lambert International Airport
₹18,360
per person
Select →
✕ Non-refundable 🔥 Last 5 seats 9 fare options
Southwest Airlines
WN-1346
15:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
7h 20m
1 Stop
⏱ TPA · 1h 10m TPA Airport
22:55
05/11/2026
STL
St Louis Lambert International Airport
₹18,861
per person
Select →
✕ Non-refundable 4 fare options
Southwest Airlines
WN-1282
15:00
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
8h 50m
1 Stop
⏱ DEN · 4h 30m DEN Airport
23:50
05/11/2026
STL
St Louis Lambert International Airport
₹18,890
per person
Select →
✕ Non-refundable 🔥 Last 5 seats 9 fare options
Southwest Airlines
WN-1346
15:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
7h 50m
1 Stop
⏱ BWI · 4h 55m BWI Airport
23:25
05/11/2026
STL
St Louis Lambert International Airport
₹18,890
per person
Select →
✕ Non-refundable 4 fare options
Southwest Airlines
WN-369
10:55
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
5h 55m
2 Stops
⏱ BNA · 0h 40m BNA Airport ⏱ JAX · 0h 50m JAX Airport
16:50
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 🔥 Last 2 seats 4 fare options
Southwest Airlines
WN-369
10:55
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
6h 45m
2 Stops
⏱ BNA · 1h 35m BNA Airport ⏱ DAL · 0h 45m DAL Airport
17:40
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 🔥 Last 5 seats 4 fare options
Southwest Airlines
WN-369
10:55
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
8h 0m
2 Stops
⏱ BNA · 1h 35m BNA Airport ⏱ MDW · 3h 0m MDW Airport
18:55
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 4 fare options
Southwest Airlines
WN-4845
05:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
7h 40m
2 Stops
⏱ BWI · 1h 10m BWI Airport ⏱ BNA · 2h 45m BNA Airport
13:15
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 4 fare options
Southwest Airlines
WN-4845
05:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
7h 40m
2 Stops
⏱ BWI · 2h 40m BWI Airport ⏱ BNA · 1h 15m BNA Airport
13:15
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 4 fare options
Southwest Airlines
WN-4845
05:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
7h 35m
2 Stops
⏱ BWI · 1h 15m BWI Airport ⏱ MCI · 2h 0m MCI Airport
13:10
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 🔥 Last 2 seats 4 fare options
Southwest Airlines
WN-4845
05:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
9h 20m
2 Stops
⏱ BWI · 1h 10m BWI Airport ⏱ ATL · 4h 0m ATL Airport
14:55
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 4 fare options
Southwest Airlines
WN-4845
05:35
05/11/2026
DTW
Detroit Metropolitan Wayne County Airport
7h 55m
2 Stops
⏱ BWI · 1h 20m BWI Airport ⏱ BOS · 1h 35m BOS Airport
13:30
05/11/2026
STL
St Louis Lambert International Airport
₹19,037
per person
Select →
✕ Non-refundable 4 fare options
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Detroit to St. Louis — what to expect when booking
The DTW–STL route is served by multiple carriers throughout the year.
Fares on this route can move quickly — a price available now may not be there 30 minutes later.
If your dates are flexible, try shifting your departure by a day or two using the date strip above.
Mid-week departures often show lower base fares compared to weekend starts on many routes.
The distance between Detroit,USA and St. Louis,USA is approximately
707.10 km .